What is the function of juxtaglomerular cells of a kidney?
Juxtaglomerular cells (JG cells), also known as granular cells are cells in the kidney that synthesize, store, and secrete the enzyme renin. They are specialized smooth muscle cells mainly in the walls of the afferent arterioles (and some in the efferent arterioles) that deliver blood to the glomerulus.
What is the function of juxtaglomerular?
The juxtaglomerular apparatus functions to maintain blood pressure and to act as a quality control mechanism to ensure proper glomerular flow rate and efficient sodium reabsorption. The urethra extends from the bladder to the surface of the body. It consists of an epithelium-lined lumen and a smooth muscle layer.
What is the function of the juxtaglomerular apparatus quizlet?
The juxtaglomerular apparatus is responsible for: regulating the rate of filtrate formation and controlling systemic blood pressure.
What is meant by juxtaglomerular apparatus?
The juxtaglomerular apparatus is a collective term referring to the cells near a structure called the glomerulus in the kidney. The juxtaglomerular cells are specialized cells that stimulate the secretion of the adrenal hormone aldosterone and play a major role in renal autoregulation, the kidney’s self-governance.
How are juxtaglomerular cells activated?
Juxtaglomerular Cells Although they are activated by prostaglandins released from the macula densa cells, they can also release renin independently of the macula densa. Baroreceptors found in the arterioles trigger renin secretion if there is a fall in blood pressure in the arterioles.
Which hormone is released when the juxtaglomerular cells of the kidney detect decreased blood flow?
Mechanism of Action. Increased renin release from the juxtaglomerular cells is caused by several conditions: reduction in renal blood flow from heart failure, blood loss, hypotension or ischemia of the kidneys, sodium diuresis (excessive sodium loss in urine), and beta-adrenergic stimulation.
What happens at the juxtaglomerular complex when low salt conditions is sensed?
When there is a decrease in the sodium concentration, less sodium is reabsorbed in the macular densa cells. The cells increase the production of nitric oxide and Prostaglandins to vasodilate the afferent arterioles and increase renin release.
What are the three components of the juxtaglomerular apparatus?
The three cellular components of the apparatus are the macula densa, extraglomerular mesangial cells, and juxtaglomerular cells (also known as granular cells)[WP].
When the juxtaglomerular cells in the kidney are they produce and secrete the enzyme?
When the juxtaglomerular cells in the kidney are, they produce and secrete the enzyme renin into the blood.
What two things make up the juxtaglomerular apparatus?
The juxtaglomerular apparatus, located in the glomerular hilum, consists of a vascular component (afferent and efferent arterioles and extraglomerular mesangium) and a tubular component (macula densa).
What happens at the Juxtaglomerular complex when low salt conditions is sensed?
How does juxtaglomerular cells detect blood pressure?
The afferent arteriole in this region contains specialised secretory cells (smooth muscle cells) called juxtaglomerular cells, that secrete renin. They monitor blood pressure, by measuring how much the arteriole wall is stretched.