What is the difference between Valium and diazepam?
Valium is known by the generic name diazepam, and it is used to treat anxiety disorders, seizure disorders, muscle tightness, and alcohol withdrawal symptoms. It has a rapid onset of action with an average time to peak concentration of one hour.
What does Valium do to the brain?
The chemical compounds known as benzodiazepines, such as Valium, calm the brain by discouraging neurons from firing.
Is diazepam a Valium?
Diazepam (Valium) is a fast-acting benzodiazepine. It slows down activity in your brain and spinal cord, to help control anxiety, muscle spasms, and seizures.
Whats stronger diazepam or lorazepam?
Diazepam and lorazepam differ in potency and in the time-course of their action. As a sedative, diazepam 10 mg is equivalent to lorazepam 2-2.5 mg. Diazepam is better absorbed after oral than after i.m. administrations but this does not apply to lorazepam.
Can lorazepam and diazepam be taken together?
Don’t take either lorazepam or diazepam – like all benzodiazepines – in conjunction with depressants, tranquilizers, or other drugs that slow brain processes. Drugs such as alcohol, barbiturates, narcotics, and tranquilizers can magnify dangerously the sedating effect of both lorazepam and diazepam.
What is the mechanism of action of diazepam?
Diazepam is a benzodiazepine tranquilliser with anticonvulsant, sedative, muscle relaxant and amnesic properties 9,10,6. Benzodiazepines, such as diazepam, bind to receptors in various regions of the brain and spinal cord. This binding increases the inhibitory effects of gamma-aminobutyric acid (GABA) 9,10,6.
What receptors does diazepam act?
That the GABAA receptor is the main target for the central actions of benzodiazepines has been known for several decades (Costa et al., 1975; Haefely et al., 1975). The mechanism by which benzodiazepines, such as diazepam (DZP), enhance GABA receptor function has been termed allosteric.
What are the metabolites of diazepam?
Diazepam is metabolized to nordiazepam, oxazepam, and temazepam; all may be detected after diazepam use.
Which is stronger lorazepam or diazepam?
Which Benzo is best for sleep?
Benzodiazepines that have been approved by the FDA for treating chronic insomnia include estazolam, flurazepam (Dalmane), temazepam (Restoril), quazepam (Doral), and triazolam (Halcion). Rapidly acting drugs with shorter half-lives (i.e., estazolam, triazolam, and temazepam) are preferred.
What is diazepam (Valium)?
Diazepam is a drug best known by the brand name Valium. Diazepam is mostly used to treat anxiety, insomnia, seizures, muscle spasms, restless leg syndrome and symptoms of alcohol and benzodiazepine withdrawal. Other uses of valium include inducing amnesia and reducing tension during surgical procedures and as pre-medication for endoscopies.
What happens if you take Valium with other medications?
Taking Valium with other drugs that make you sleepy or slow your breathing can cause dangerous side effects or death. Ask your doctor before taking a sleeping pill, opioid pain medicine, prescription cough medicine, a muscle relaxer, or medicine for anxiety, depression, or seizures.
How does Valium work to treat anxiety?
Valium also affects areas on the limbic system, the thalamus and hypothalamus contributing to the relief of anxiety. Valium is long lasting and can be given intravenously, orally, intra muscularly and also as a rectal suppository. Due to Valium producing dependence and tolerance, short term use is recommended.
Do benzodiazepines like Valium and Xanax cause brain damage?
Last week, Britain’s Independent newspaper published a bombshell for psychiatry and medicine: the country’s Medical Research Council had sat on warnings voiced 30 years earlier that benzodiazepines such as Valium and Xanax can cause brain damage.