Which drugs cause a reaction similar to disulfiram?
Examples of drugs that have been reported to produce disulfaram-like reactions include metronidazole (Flagyl and other brands), trimethoprim-sulfamethoxazole (Bactrim, Bactrim DS), tinidazole, chlorpropamide (Diabinese), tolbutamide, and others.
What type of drug interaction is related to the distribution of the medications?
pharmacokinetic – defined as an alteration in the absorption, distribution, metabolism or excretion of one drug by another. This is the most common type of drug interaction. pharmacodynamic – where the drug affects the action or effect of the other drug.
How quickly does naltrexone work?
Naltrexone is approved for use in the treatment of opioid use disorder and alcohol use disorder. Oral naltrexone is well-absorbed and will usually begin working within one hour after a dose. Intramuscular naltrexone is an extended-release formulation and has two peaks, first at 2 hours then again 2 to 3 days later.
How does alcohol affect metoprolol?
Metoprolol and Alcohol Interaction Alcohol can also reduce your blood pressure. When you combine drinking alcohol with metoprolol, the additive effect on the blood pressure can cause it to drop to a dangerously low level. This condition is called hypotension.
What are the two types of drug-alcohol interactions?
Two types of alcohol- medication interactions exist: (1) pharmacokinetic interactions, in which alcohol interferes with the metabolism of the medication, and (2) pharmacodynamic interactions, in which alcohol enhances the effects of the medication, particularly in the central nervous system (e.g., sedation).
What happens when you drink alcohol and take other drugs?
When alcohol is consumed with other drugs that primarily use this enzyme for breakdown (metabolism) and excretion, blood levels of the other drug may theoretically increase, leading to increased side effects and toxicity. An example of this is with the drug interaction between warfarin and alcohol.
Are there any drugs that act like alcohol?
Scientists have already created drugs that act like alcohol on the brain. Alcoholics who are trying to quit can take a class of drugs called benzodiazepines.
Can sedative medications interfere with alcohol?
For example, the sedative effects of both alcohol and sedative medications can enhance each other (i.e., the effects are addi- tive), thereby seriously impairing a person’s ability to drive or operate other types of machinery. Most studies assessing alcohol- medication interactions focus on the effects of chronic heavy drinking.