Is estrogen positive breast cancer slow growing?
Estrogen receptor/progesterone receptor (ER/PR) positive breast cancers tend to grow more slowly than ER/PR negative cancers, and are more likely to respond to hormone therapy.
What does it mean if your breast cancer is estrogen positive?
Hormone status of breast cancers includes: Estrogen receptor (ER) positive. The cells of this type of breast cancer have receptors that allow them to use the hormone estrogen to grow. Treatment with anti-estrogen hormone (endocrine) therapy can block the growth of the cancer cells.
Are most breast cancer estrogen positive?
About 80\% of all breast cancers are “ER-positive.” That means the cancer cells grow in response to the hormone estrogen. About 65\% of these are also “PR-positive.” They grow in response to another hormone, progesterone.
Is estrogen receptor negative good or bad?
Estrogen receptor (ER)-negative breast cancers are a group of tumors with poor prognosis and fewer cancer prevention and treatment strategies compared to ER-positive tumors.
Is estrogen receptor positive a good thing?
Hormone receptor-positive cancers tend to grow more slowly than those that are hormone receptor-negative. Women with hormone receptor-positive cancers tend to have a better outlook in the short-term, but these cancers can sometimes come back many years after treatment.
Is it better to be HER2-positive or triple negative?
Conclusions: The triple negative subtype has the worst survival regardless of stage. HER2-positive cancers are heterogeneous and not all have poor survival. ER and PR must be considered. ER status appears to influence 5-year survival more than HER2 status.
What type of breast cancer is most likely to metastasize?
While all types of breast cancer have the potential to metastasize, human epidermal growth factor receptor 2 (HER2)-positive and triple-negative cancers are more aggressive and more likely to metastasize faster than the other types.
Is it better to be hormone receptor positive or negative?
What does positive estrogen receptor mean?
Describes cells that have a protein that binds to the hormone estrogen. Cancer cells that are estrogen receptor positive may need estrogen to grow. These cells may stop growing or die when treated with substances that block the binding and actions of estrogen. Also called ER positive.
Is hormone therapy better than chemotherapy?
Contrary to the commonly held view, 2 years after diagnosis, hormone therapy, a highly effective breast cancer treatment worsens quality of life to a greater extent and for a longer time, especially in menopausal patients. The deleterious effects of chemotherapy are more transient.
What type of breast cancer is most likely to recur?
Younger age. Younger people, particularly those under age 35 at the time of their original breast cancer diagnosis, face a higher risk of recurrent breast cancer. Inflammatory breast cancer. People with inflammatory breast cancer have a higher risk of local recurrence.
How does estrogen affect breast cancer?
The female hormone estrogen is thought to play a role in the risk of breast cancer and perhaps some other cancers of the reproductive system; tumors grow rapidly in the presence of the hormone, thus the risk of breast cancer probably fluctuates with changes in estrogen levels throughout a woman’s life.
Does estrogen increase risk of breast cancer?
In March 2004, it was concluded from the WHI study that those taking estrogen only had no increased risk of breast cancer or heart disease; however, estrogen does appear to increase one’s risk of blood clots and stroke. If you are considering HRT to relieve your menopausal symptoms, talk to your doctor to discuss the risks and benefits.
What women with breast cancer should know about estrogens?
The Role of Estrogen in Breast Cancer.
What is the link between estrogen and cancer?
A link between breast cancer and hormones is clear. Researchers think that the greater a woman’s exposure to the hormone estrogen, the more susceptible she is to breast cancer. Estrogen tells cells to divide; the more the cells divide, the more likely they are to be abnormal in some way, possibly becoming cancerous.