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What are the side effects of polypharmacy?

Posted on August 24, 2022 by Author

What are the side effects of polypharmacy?

Possible symptoms of polypharmacy include:

  • Loss of appetite.
  • Falls.
  • Confusion.
  • Weakness.
  • Tremors.
  • Dizziness.
  • Anxiety.
  • Depression.

What are three of the negative outcomes of polypharmacy?

Unfortunately, there are many negative consequences associated with polypharmacy. , Specifically, the burden of taking multiple medications has been associated with greater health care costs and an increased risk of adverse drug events (ADEs), drug-interactions, medication non-adherence, reduced functional capacity and …

What are the impacts of polypharmacy on the older person on the healthcare system?

Polypharmacy increases risk of adverse events and errors Taking multiple medications – known as ‘polypharmacy’ – increases the risk of medications being implicated in hospital admissions, particularly when an older person presents with falls, confusion or incontinence3.

Is polypharmacy good or bad?

Polypharmacy is an area of concern for elderly because of several reasons. Elderly people are at a greater risk for adverse drug reactions (ADRs) because of the metabolic changes and reduced drug clearance associated with ageing; this risk is furthermore exacerbated by increasing the number of drugs used.

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Is polypharmacy a problem?

Polypharmacy increases the risk of adverse reactions to medications. The more drugs, the higher the risk of drug interactions. Research has shown that patients taking five to nine medications have a 50\% chance of an adverse drug interaction, increasing to 100\% when they are taking 20 or more medications.

Who is most affected by polypharmacy?

Polypharmacy is more common among older adults, many of whom have multiple chronic conditions (MCC), defined as two or more chronic conditions such as arthritis, asthma, chronic obstructive pulmonary disease, coronary heart disease, depression, diabetes, and hypertension.

Can polypharmacy be problematic?

As noted by Guthrie et al. [5] polypharmacy is “potentially problematic rather than always inappropriate” and, as such, assessments of prescribing appropriateness need to extend beyond the number of drugs prescribed and consider co-existing medical conditions in differentiating between ‘many’ and ‘too many’ medicines.

Why is polypharmacy a problem?

Inappropriate polypharmacy — the use of excessive or unnecessary medications — increases the risk of adverse drug effects, including falls and cognitive impairment, harmful drug interactions, and drug-disease interactions, in which a medication prescribed to treat one condition worsens another or causes a new one.

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Is polypharmacy harmful to heart failure patients?

Division of Cardiology/Department of Medicine (P.G.), Weill Cornell Medicine, New York, NY. Despite potential harm that can result from polypharmacy, real-world data on polypharmacy in the setting of heart failure (HF) are limited.

Why is polypharmacy a growing concern for older adults?

This is a growing concern for older adults. Polypharmacy is more common among older adults, many of whom have multiple chronic conditions (MCC), defined as two or more chronic conditions such as arthritis, asthma, chronic obstructive pulmonary disease, coronary heart disease, depression, diabetes, and hypertension.

What is polypharmacy and why is it important?

Polypharmacy, defined as regular use of at least five medications, is common in older adults and younger at-risk populations and increases the risk of adverse medical outcomes. There are several…

What is the prevalence of polypharmacy in older adults with heart failure?

The prevalence of polypharmacy increases after a hospitalization for heart failure, and has increased between 2003 and 2014. The majority of medications prescribed to older adults with heart failure are noncardiovascular medications. What are the Clinical Implications?

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